Genomic characterization of antimicrobialresistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombia

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dc.audienceInvestigadorspa
dc.audience.contentCientíficospa
dc.contributor.authorGarcía Álvarez, María Isabel
dc.contributor.authorVidal, Juana L.
dc.contributor.authorDonado Godoy, Pilar
dc.contributor.authorSmith, Jared
dc.contributor.authorShariat, Nikki
dc.contributor.authorValencia, María Fernanda
dc.contributor.authorGómez Osorio, Luis M.
dc.contributor.authorLópez Osorio, Sara
dc.contributor.authorChaparro Gutiérrez, Jenny J.
dc.coverage.countryColombiaspa
dc.coverage.researchcenterC.I Tibaitatáspa
dc.date.accessioned2025-08-28T19:44:35Z
dc.date.available2025-08-28T19:44:35Z
dc.date.created2025-01
dc.date.issued2025
dc.description.abstractOccurrence of antimicrobial-resistant Salmonella strains has been reported worldwide, because of inappropriate use of antimicrobial products in either humans or animals. The presence of multidrug resistant Salmonella in pig production systems had been reported in Antioquia, Colombia. Aim: To identify antimicrobial resistance genes (ARG) in different Salmonella spp. strains isolated from pig productions in Antioquia, Colombia. Methods: Samples were received at the Diagnostic Unit of the Faculty of Agrarian Sciences at the University of Antioquia, from January 1, 2019, to January 2021. A total of 28 isolates of Salmonella spp. were included, which presented phenotypic resistance to more than one antibiotic used in pig farms. Whole genome sequencing (WGS) was performed in the Unit of Genomic of Agrosavia using an automated pipeline from the GHRU- Sanger Institute, employing the Illumina MiSeq platform. Results: WGS revealed 34 ARGs among these isolates. In 25 isolates (89%) more than two ARGs were found. Genes encoding resistance were found for 10 different groups of antibiotics (beta-lactam, aminoglycosides, chloramphenicol, rifampicins, lincosamides, fluoroquinolones, tetracyclines, sulfonamides and trimethoprim). The most frequently observed MDR profile in Typhimurium isolates was AMP-CEX-CEP-CEF-EFT-CEQ-FLU-ENR-TE-FFC-SXT.spa
dc.description.productionsystemsPorciculturaspa
dc.format.mimetypeapplication/pdf
dc.identifierhttps://pubmed.ncbi.nlm.nih.gov/39888971/spa
dc.identifier.doi10.1371/journal.pntd.0012830spa
dc.identifier.instnameinstname:Corporación colombiana de investigación agropecuaria AGROSAVIA
dc.identifier.issn1935-2727
dc.identifier.reponamereponame:Biblioteca Digital Agropecuaria de Colombia
dc.identifier.urihttp://hdl.handle.net/20.500.12324/41148
dc.language.isoengspa
dc.publisherPublic Library of Sciencespa
dc.publisher.placeBogotá (Colombia)spa
dc.relation.citationendpage18spa
dc.relation.citationissue1spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume19spa
dc.relation.ispartofjournalPLoS Neglected Tropical Diseasesspa
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dc.relation.referencesHernández-Ledesma A, Cabrera-Díaz E, Arvizu-Medrano SM, Gómez-Baltazar A, Hernández- Iturriaga M, Godínez-Oviedo A, et al. Virulence and antimicrobial resistance profiles of Salmonella enterica isolated from foods, humans, and the environment in Mexico. Int J of Food Microbiol. 2023;391:110135. https://doi.org/10.1016/j.ijfoodmicro.2023.110135 PMID: 36827747spa
dc.relation.referencesBalasubramanian R, Im J, Lee J-S, Jeon HJ, Mogeni OD, Kim JH, et al. The global burden and epidemiology of invasive non-typhoidal Salmonella infections. Hum Vaccin Immunother. 2019;15(6):1421–6. https://doi.org/10.1080/21645515.2018.1504717 PMID: 30081708spa
dc.rightsAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourcePLoS Neglected Tropical Diseases; Vol. 19, Núm. 1 (2025): PLoS Neglected Tropical Diseases (Jan.);p. 1 - 18.spa
dc.subject.agrovocSalmonellaspa
dc.subject.agrovocAntimicrobianospa
dc.subject.agrovocCerdo cebónspa
dc.subject.agrovocExplotación agrariaspa
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_6757spa
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_509spa
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_59e0f842spa
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_2809spa
dc.subject.faoEnfermedades de los animales - L73spa
dc.subject.redGanadería y especies menoresspa
dc.titleGenomic characterization of antimicrobialresistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombiaspa
dc.title.translatedGenomic characterization of antimicrobialresistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombiaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.localArtículo científicospa
dc.type.localengarticleeng
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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