Expresión diferencial durante la interacción Solanum tuberosum - Phytophthora infestans

dc.audienceInvestigadorspa
dc.audience.contentCientíficospa
dc.contributor.authorMonsalve Fonnegra, Zulma Isabel
dc.contributor.authorMonsalve Restrepo, María Isabel
dc.contributor.authorUrrea Trujillo, Aura Inés
dc.contributor.authorZapata, José Luis
dc.coverage.countryColombiaspa
dc.coverage.researchcenterC.I La Selvaspa
dc.date.accessioned2025-06-03T19:45:26Z
dc.date.available2025-06-03T19:45:26Z
dc.date.created2012-07
dc.date.issued2012
dc.description.abstractLa papa (Solanum tuberosum L.) es el cuarto cultivo más importante a nivel mundial y es el producto agrícola con mayor demanda de fungicidas, insecticidas y fertilizantes químicos. Las pérdidas mundiales ocasionadas por Phytophthora infestans (Mont.) de Bary en este cultivo, ascienden a 6,7 billones de dólares al año y su control químico genera un aumento en los costos, perjudica la salud humana y el ambiente. Todo esto justifica la búsqueda constante de mecanismos alternativos para el control de la enfermedad, entre ellos la obtención de variedades resistentes mediante cisgenesis usando genotipos silvestres. Como un aporte en este sentido, y dada la falta de conocimiento de lo que controla y constituye la diferencia entre una respuesta compatible e incompatible, en el presente estudio se compararon los perfiles de expresión génica obtenidos mediante Despliegue Diferencial de variedades resistentes y susceptibles durante su interacción con P. infestans.spa
dc.description.productionsystemsPapaspa
dc.description.scientificnameSolanum tuberosum
dc.description.sponsorshipGeneración de marcas de secuencias expresadas - ESTSspa
dc.description.sponsorshipUniversidad de Antioquia - UdeAspa
dc.format.mimetypeapplication/pdf
dc.identifierhttps://repositorio.unal.edu.co/handle/unal/42178
dc.identifier.instnameinstname:Corporación colombiana de investigación agropecuaria AGROSAVIAspa
dc.identifier.reponamereponame:Biblioteca Digital Agropecuaria de Colombiaspa
dc.identifier.urihttp://hdl.handle.net/20.500.12324/40974
dc.language.isospa
dc.publisherUniversidad Nacional de Colombia - UNALspa
dc.publisher.placeBogotá (Colombia)spa
dc.relation.citationendpage92
dc.relation.citationissue1
dc.relation.citationstartpage77
dc.relation.citationvolume14
dc.relation.ispartofjournalRevista Colombiana de Biotecnologíaspa
dc.relation.referencesAbad, G., Abad, J., Ochoa, C. 1995. Historical and scientific evidence that supports the modern theory of the Peruvian Andes as the centre of origin of Phytophthora infestans. En: LJ Dowley, E Bannon, LR Cooke, T Keane, and E O´Sullivan (eds.). Phytophthora infestans 150. Ireland: Boole Press Ltd. pp. 239-245.spa
dc.relation.referencesAbu-Nada, Y., Kushalappa, A.C., Marshall, W.D., Al-Mughrabi, K., Murphy, A. 2007. Temporal dynamics of pathogenesis-related metabolites and their plausible pathways of induction in potato leaves following inoculation with Phytophthora infestans. European Journal of Plant Pathology 118: 375-391.spa
dc.relation.referencesAgrios, G. 2005. Plant pathology. 5th ed. Nueva York: Editorial Elsevier Academic Press. pp. 922.spa
dc.relation.referencesAgrocadenas. 2006. La cadena de la papa en colombia. Una mirada global de su estructura y dinámica (1991-2005) [sitio web]. Bogotá DC (Colombia): Ministerio de agricultura y desarrollo rural. Documento de trabajo N° 100; Enero de 2006 [fecha de acceso: Febrero de 2010]. Disponible en: http://www.agrocadenas.gov.co .spa
dc.relation.referencesBailey, A. M., Muñoz-Sánchez, C. I., Martínez-Hernández, P., Manríquez-Escamilla, M. 2001. Detection of Additional Gene Products Induced by the Interaction between Phytophthora capsici and its host Capsicum annuum and the identification of an Elicitin-Encoding Gene. Revista Mexicana de Fitopatología 19: 22- 31.spa
dc.relation.referencesBallesteros, D.C., Gómez, G., Delgado, M.C., Álvarez, M.F., Juyó, D., Cuéllar, D., y Mosquera, T. 2010. Posible presencia de un gen R1 en germoplasma de Solanum tuberosum Grupo Phureja. Agronomía Colombiana 28:137-146.spa
dc.relation.referencesBauer, D., Warthoe, P., Rohde, M., Strauss, M. 1994. Detection and differential display of expressed genes by DDRT-PCR. PCR methods and applications 4: S97-108.spa
dc.relation.referencesBeligni, M.V., Laxalt, A.M., Lamattina, L. 1999. Temporal and spatial patterns of GAPDHc mRNA accumulation during an incompatible potato- Phytophthora infestans interaction. Comparison with a compatible interaction. Physiologia Plantarum 105: 280-287.spa
dc.relation.referencesBetancourth, C., Portilla, E., Salas, H. 2008. Evaluación de la reacción de nueve genotipos de papa (Solanum tuberosum subsp. andigena) al ataque de Phytophthora infestans (Mont) de Bary. Agronomía Colombiana 26: 411-416.spa
dc.relation.referencesBormann, C., Rickert, A.M., Castillo, R.A., Paal, J., Lübeck, J., Strahwald, J., Buhr, K., Gebhardt, C. 2004. Tagging quantitative trait loci for maturity-corrected late blight resistance in tetraploid potato with PCR-based candidate gene markers. Molecular plant-microbe interactions 17: 1126-1138.spa
dc.relation.referencesCevipapa. 2010. [sitio web]. Colombia. [Fecha de acceso: Febrero 6 de 2010]. Disponible en: http://www.cevipapa.org.co/spa
dc.relation.referencesCastro-Mercado, E. y García-Pineda, E. La inmunidad innata en las : una batalla molecular entre receptores y estimuladores. Revista Biológicas 11: 43- 47.spa
dc.relation.referencesCollard, B., Jahufer, M., Brouwer, J., Pang, E. 2005. An introduction to markers, quantitative trait loci (QTL) mapping and marker-assisted selection for crop improvement: The basic concepts. Euphytica 142: 169-196.spa
dc.relation.referencesColon, L.T., Jansen, R.C., Budding, D.J. 1995a. Partial resistance to late blight (Phytophthora infestans) in hybrid progenies of four South American Solanum species crossed with diploid S. tuberosum. Theoretical and Applied Genetics 90: 691-698.spa
dc.relation.referencesColon, L.T., Turkensteen, L.J., Prummel, W., Budding, D.J., Hoogendoorn, J. 1995. Durable resistance to late blight (Phytophthora infestans) in old potato cultivars. European Journal of Plant Pathology 101: 387-397.spa
dc.relation.referencesCornelissen, B.J.C., Melchers, L.S. 1993. Strategies for Control of Fungal Diseases with Transgenic Plants. Plant physiology 101: 709-712.spa
dc.relation.referencesCorrea, J., Monsalve, Z. 2005. Patrón de expresión genética durante la interacción de Solanum tuberosum var. Parda pastusa y var. Tuquerreña con Phytophthora insfestans. Trabajo de Grado. Facultad de Ciencias Exactas, Instituto de Biología, Universidad de Antioquia, Medellin, Colombia.spa
dc.relation.referencesDavidian, J.C., Kopriva, S. 2010. Regulation of Sulfate Uptake and Assimilation — the Same or Not the Same? Molecular Plant 3 (2): 314-325.spa
dc.relation.referencesDonaire, E. R., García, W. 2006. Alternativa agroecológica para el control del tizón tardío, Phytophthora infestans, de la papa en Colomi - Bolivia. Acta Nova 3: 564-577.spa
dc.relation.referencesDíaz, M., Fajardo, D.A., Moreno, J.D., García, C., Nuñez, V.M. 2003. Identificación de Genes R1 y R2 que confieren resistencia a Phytophthora infestans en genotipos colombianos de papa. Revista Colombiana de Biotecnología 5: 40-50.spa
dc.relation.referencesDubey, M.K., Shasany, A.K., Dhawan, O.P., Shukla, A.K., Khanuja, S.P.S. 2009. Genetic Variation revealed in the chloroplast-encoded RNA polymerase β´ Subunit of downy mildew – resistant genotype of opium poppy. Journal of Heredity 100 (1): 76-85.spa
dc.relation.referencesElliott, F. 1996. Mejoramiento de plantas citogenéticas. México: Continental.spa
dc.relation.referencesEstrada, N. 2000. Mejoramiento genético de la papa para resistencia al tizón.Papas Colombianas 2000 con el mejor entorno ambiental 3: 38-39.spa
dc.relation.referencesFAO. 2010. Crops statistics database. Disponible en: http://faostat.fao.org/spa
dc.relation.referencesFreytag, S., Arabatzis, N., Hahlbrock, K., Schmelzer, E. 1994. Reversible cytoplasmic rearrangements precede wall apposition, hypersensitive cell death and defense-related gene activation in potato/Phytophthora infestans interactions. Planta 194: 123-135.spa
dc.relation.referencesFry, W. 2008. Phytophthora infestans: the plant (and R gene) destroyer. Molecular Plant Pathology 9: 385-402.spa
dc.relation.referencesGiraldo, D., Juarez, H., Pérez, W., Trebejo, I., Yzarra, W., Forbes, G. 2010. Severity of the potato late blight (Phytophthora infestans) in agricultural areas of Peru associated with climate change. Revista Peruana Geo-Atmosférica 67: 56-67.spa
dc.relation.referencesGrupo de Investigación de la Papa, Facultad de Agronomía de la Universidad Nacional de Colombia. Catálogo de variedades colombianas. [sitio web]. [fecha de acceso: Febrero de 2010]. Disponible en: http://papaunc.com/catalogoExtendido.shtml?x=44spa
dc.relation.referencesGuzmán, J., Thurston, H.D., Heidrick, L.E. 1960. Resultados sobre la naturaleza de la resistencia parcial de tres clones de papa a Phytophthora infestans (Mont) De Bary. Agricultura Tropical 16: 89-99.spa
dc.relation.referencesHaas, F.H., Heeg, C., Queiroz, R., Bauer, A., Wirtz, M., Hell, R. 2008. Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells. Plant physiology 148 (2): 1055-1067.spa
dc.relation.referencesHaas, B., Kamoun, S., Zody, M.C., Jiang, R.H., Handsaker, R.E., Cano, L.M., Grabherr, M. et al., 2009. Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans. Nature 461: 393-398.spa
dc.relation.referencesHarms, K., Ballmoos, P.V., Brunold, C., Höfgen, R., Hesse, H. 2000. Expression of a bacterial serine acetyltransferase in transgenic potato plants leads to increased levels of cysteine and glutathione. The Plant Journal 22 (4): 335-343.spa
dc.relation.referencesHenriquez, M.A., Daayf, F. 2010. Identification and cloning of differentially expressed genes involved in the interaction between potato and Phytophthora infestans using a subtractive hybridization and cDNA-AFLP combinational approach. Journal of integrative plant biology 52: 453-467.spa
dc.relation.referencesIbrahim, A., Hedley, P.E., Cardle, L., Kruger, W., Marshall, D.F., Muehlbauer, G.J., Waugh, R. 2005. A comparative analysis of transcript abundance using SAGE and Affymetrix arrays. Functional & integrative genomics 5: 163-174.spa
dc.relation.referencesJacobs, M., Vosman, B., Vleeshouwers, V., Visser, R.G.F., Henken, B., Van den Berg, R. 2010. A novel approach to locate Phytophthora infestans resistance genes on the potato genetic map. Theoretical and applied genetics. 120: 785-796.spa
dc.relation.referencesJagoueix-Eveillard, S., Tarendeau, F., Guolter, K., Danet, J.L., Bové, J.M., Garnier, M. 2001. Catharanthus roseus genes regulated differentially by mollicute infections. Molecular plant-microbe interactions 14: 225-233.spa
dc.relation.referencesJames, R., Fry, W. 1983. Potential for Phytophthora infestans populations to adapt to potato cultivars with rate-reducing resistance. Phytopathology 73: 984-988.spa
dc.relation.referencesJaramillo, S. 2003. Monografía sobre Phytophthora infestans (Mont) De Bary. Facultad de Ciencias Agropecuarias, Universidad Nacional de Colombia, Medellin, Colombia.spa
dc.relation.referencesJimenez, J., Chaparro-Giraldo, A., Blanco, J. 2009. Evaluación de diferentes combinaciones fitohormonales en la regeneración de Solanum tuberosum (Solanaceae) Var. Pastusa Suprema a partir de explantes internodales. Revista Colombiana de Biotecnología 11: 67-74.spa
dc.relation.referencesJoos, J.H., Hahlbrock, K. 1992. Phenylalanine ammonia-lyase in potato (Solanum tuberosum L.). European Journal of Biochemistry 204:621-629.spa
dc.relation.referencesKim, H.L. 2003. Comparison of oligonucleotide-microarray and serial analysis of gene expression (SAGE) in transcript profiling analysis of megakaryocytes derived from CD34+ cells. Experimental & molecular medicine 35: 460-466.spa
dc.relation.referencesKariola, T., Brader, G., Li, J., Tapio-Palva, E. 2005. Chlorophyllase 1 , a Damage control enzyme, affects the balance between defense pathways in plants. The Plant Cell 17 (1): 282-294.spa
dc.relation.referencesKopriva, S., Mugford, S.G., Matthewman, C., Koprivova, A. 2009. Plant sulfate assimilation genes: redundancy versus specialization. Plant Cell Reports 28 (12): 1769-1780.spa
dc.relation.referencesLandeo, J.A., Gastelo, M., Beltran, G., Diaz, L. 2000. Quantifying genetic variance for horizontal resistance to late blight in potato breeding population B3C1. CIP Program report 1999–2000, International Potato Centre, Peru. pp 63–68.spa
dc.relation.referencesLawton, M.A., Lamb, C.J. 1987. Transcriptional activation of plant defense genes by fungal elicitor, wounding and infection. Molecular and Cellular Biology 7: 335-341.spa
dc.relation.referencesLeonards-Schippers, C., Gieffers, W., Schäfer-Pregl, R., Ritter, E., Knapp, S.J., Salamini, F., Gebhardt, C., 1994. Quantitative resistance to Phytophthora infestans in potato: a case study for QTL mapping in an allogamous plant species. Genetics 137: 67-77.spa
dc.relation.referencesLi, Y., Tian, Z., Liu, J., Xie, C. 2009. Comparative cDNA-AFLP analysis reveals thatdl--amino-butyric acid induces resistance through early activation of the host-defense genes in potato. Physiologia Plantarum 136: 19-29.spa
dc.relation.referencesLiang, P., Meade, J.D., Pardee, A.B. 2006. Differential display methods and protocols. En Methods in molecular biology. 2nd ed. Towota: NJ Humana Press.spa
dc.relation.referencesLiang, P. 2002. SAGE Genie: a suite with panoramic view of gene expression. Proceedings of the National Academy of Sciences of the United States of America 99: 11547-11548.spa
dc.relation.referencesLindqvist-kreuze, H., Carbajulca, D., Gonzalez-escobedo, G. 2010. Comparison of transcript profiles in late blight-challenged Solanum cajamarquense and B3C1 potato clones. Molecular Plant Pathology 11: 513-530.spa
dc.relation.referencesLópez, A., Chaparro, A. 2007. Propuesta de un sistema de transformación de plantas de papa (Solanum tuberosum sp. andigena var. Pastusa suprema) mediado por Agrobacterium tumefaciens.” Agronomía Colombiana 25: 16-25.spa
dc.relation.referencesLópez-Martín, M. C., Romero, L. C., Gotor, C. 2008. Cytosolic cysteine in redox signaling. Plant Physiology 3 (10): 880-881.spa
dc.relation.referencesMalcolmson, J.F., Black, W. 1966. New R genes in Solanum demissum lindl. and their complementary races of Phytophthora infestans (Mont.) de Bary. Euphytica 15: 199-203.spa
dc.relation.referencesMaldonado, L.Y., Delgado, M. C., García,C. Estudio de la estructura genetica de las poblaciones de Phytophthora infestans en las regiones productoras de papa en Colombia [sitio web]. [fecha de acceso: Febrero de 2010]. Disponible en: http://www. redepapa.org/infestans3.pdf.spa
dc.relation.referencesMartinez, E.P., Osorio, J.A. 2007. Estudios preliminares para la producción de un biosurfactante bacteriano activo contra Phytophthora infestans (Mont.) De Bary. Revista Corpoica – Ciencia y Tecnología Agropecuaria 8: 5-16.spa
dc.relation.referencesMartini, N., Egen, M., Rüntz, I., Strittmatter, G. 1993. Promoter sequences of a potato pathogenesis-related gene mediate transcriptional activation selectively upon fungal infection. Molecular & general genetics 236: 179-186.spa
dc.relation.referencesMcDowell, J.M., Woffenden, B.J. 2003. Plant disease resistance genes: recent insights and potential applications. Trends in Biotechnology 21: 178-183.spa
dc.relation.referencesMosquera, T., Fenández, C., Martínez, L., Acuña, A.,Cuéllar, D. 2008. Genética de la resistencia de la papa (Solanum tuberosum) a patógenos. Estado de arte. Agronomia Colombiana 26: 7-15.spa
dc.relation.referencesMüller, K.O., Black, B. 1952. Potato breeding for resistance to late blight and virus disease during the last hundred years. Zeitschrift fur Pflanzenzuchtung 31: 225–236.spa
dc.relation.referencesNürnberger, T., Lipka, V. 2005. Non-host resistance in plants: new insights into an old phenomenon. Molecular Plant Pathology 6: 335-345.spa
dc.relation.referencesOjito-Ramos, K. y Portal, O. 2010. Introducción al sistema inmune de las plantas. Biotecnología Vegetal 10 (1): 3-19.spa
dc.relation.referencesPatino, W.D., Mian, O., Hwang, P.M. 2002. Serial Analysis of Gene Expression: Technical Considerations and Applications to Cardiovascular Biology. Circulation Research 9: 565-569.spa
dc.relation.referencesPinzón, A.,Barreto, E., Bernal, A., Achenie, L., González-Barrios, A.F., Isea, R., Restrepo, S. 2009. Computational models in plant-pathogen interactions: the case of Phytophthora infestans. Theoretical biology & medical modelling 6: 24spa
dc.relation.referencesRestrepo, S., Myers, K.L, Pozo, O., Martin, G.B., Hart, A.L., Buell, C.R., Fry, W.E., Smart, C.D. 2005. Gene profiling of a compatible interaction between Phytophthora infestans and Solanum tuberosum suggests a role for carbonic anhydrase. Molecular plant-microbe interactions 18: 913-922.spa
dc.relation.referencesRiemenschneider, A., Riedel, K., Hoefgen, R., Papenbrock, J., Hesse, H. 2005. Impact of reduced O-Acetylserine ( thiol ) lyase isoform contents on potato plant metabolism. Plant Physiology 137 (3): 892-900.spa
dc.relation.referencesRodriguez, E. 2000. Efecto de la combinación de un fungicida protectante y la resistencia poligénica a Phytophthora infestans en el manejo de la gota en papa. Universidad Nacional de Colombia, Bogotá, Colombia.spa
dc.relation.referencesRos, B., Mohler, V., Wenzel, G., Thümmler, F. 2008. Phytophthora infestans-triggered response of growth- and defense-related genes in potato cultivars with different levels of resistance under the influence of nitrogen availability. Physiologia Plantarum 133: 386-396.spa
dc.relation.referencesRos, B., Thümmler, F., Wenzel, G. 2005. Comparative analysis of Phytophthora infestans induced gene expression in potato cultivars with different levels of resistance. Plant biology 7: 686-693.spa
dc.relation.referencesSambrook, J., Fritsch, E., Maniatis, T. 1989. Molecular cloning, a laboratory manual. 2th Edtion, United States, Cold Spring Harbor Laboratory Press, pp. 6.46-6.48.spa
dc.relation.referencesSamen, F., Abu-El, M., Secor, G.A., Gudmestad, N.C. 2003. Variability in Virulence Among Asexual Progenies of Phytophthora infestans. Phytopathology 93: 293-304.spa
dc.relation.referencesSchick, R.E., Schick, E., Haussdorfer, M. 1958. Ein Beitrag zur physiologischen spezialisierun von Phytophthora infestans. Phytopathologische Zeitschrift 31: 225-236.spa
dc.relation.referencesStein, J., Liang, P. 2002. Differential display technology: a general guide. Cellular and Molecular Life sciences 59: 1235- 1240.spa
dc.relation.referencesStuiver, M.H., Custers, J.H. 2001. Engineering disease resistance in plants. Nature 411: 865-868.spa
dc.relation.referencesTorres, H. 2002. Manual de las enfermedades más importantes de la papa en el Perú [sitio web]. Centro Internacional de la Papa. Lima, Perú [fecha de acceso: Febrero 2010]. Disponible en: http://www.cipotato.org/csd/materials/htorres/HTorresTT.pdfspa
dc.relation.referencesTrognitz, F., Manosalva, P., Gysin, R., Niñio-Liu, D., Simon, R., Herrera, M.R., Trognitz, B., Ghislain, M., Nelson, R. 2002. Plant defense genes associated with quantitative resistance to potatospa
dc.relation.referenceslate blight in Solanum phureja x dihaploid S. tuberosum hybrids. Molecular plant-microbe interactions (6): 587-597.spa
dc.relation.referencesTroxler, R.F., Zhang, F., Hu, J., Bogorad, L. 1994. Evidence that sigma factors are components of chloroplast RNA polymerase. Plant Physiology 104 (2): 753-759.spa
dc.relation.referencesTurkensteen, L.J. 1993. Durable resistance of potatoes against Phytophthora infestans. En T Jacobs and JE Parlevliet (eds.). Durability of Disease Resistance. Dordrecht: The Netherlands: Kluwer Academic Publishers. pp. 115-124.spa
dc.relation.referencesVelculescu, V. E., Zhang, L., Vogelstein, B., Kinzler, KW. 1995. Serial analysis of gene expression. Science 270: 484-487.spa
dc.relation.referencesVillareal, H.J., Porras, P.D., Santa, A., Lagoeyte, J., Muñoz, D. 2007. Costos de producción de papa en las principales zonas productoras de colombia. Federación Colombiana de Productores de Papa. Bogotá.spa
dc.relation.referencesVogel, J.O., Raab, T.K., Schiff, C., Somerville, S.C. 2006. PMR6, a Pectate lyase–like gene required for powdery mildew susceptibility in Arabidopsis. Plant cell 14: 2095–2106.spa
dc.relation.referencesWang, X., El Hadrami, A., Adam, L.R., Daayf, F. 2008. Differential activation and suppression of potato defence responses by Phytophthora infestans isolates representing US-1 and US-8 genotypes. Plant Pathology 57: 1026-1037.spa
dc.relation.referencesWastie, R.L. 1991. Breeding for resistance. En: DS Ingram and PH Williams (eds.). Phytophthora infestans, the cause of late blight of potato. Advances in Plant Pathology. London: Academic Press. pp.193-224.spa
dc.relation.referencesWirtz, M., Hell, R. 2006. Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties. Journal of Plant Physiology 163 (3): 273-286.spa
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceRev. Colomb. Biotecnol; Vol. 14, Núm. 1 (2012):Rev. Colomb. Biotecnol (Jul.);p. 77-92.spa
dc.subject.agrovocSolanum tuberosumspa
dc.subject.agrovocFungicidaspa
dc.subject.agrovocControl de plagasspa
dc.subject.agrovocControl químicospa
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_7221
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_3146
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_5726
dc.subject.agrovocurihttp://aims.fao.org/aos/agrovoc/c_1514
dc.subject.faoPlagas de las plantas - H10spa
dc.subject.redRaíces y tubérculosspa
dc.titleExpresión diferencial durante la interacción Solanum tuberosum - Phytophthora infestansspa
dc.title.translatedDifferential expression during Solanum tuberosum - Phytophthora infestans interactionspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.type.driverinfo:eu-repo/semantics/article
dc.type.localArtículo científicospa
dc.type.localengarticleeng
dc.type.redcolhttps://purl.org/redcol/resource_type/ART
dc.type.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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